Something that causes thoughtlessness, forgetfulness, unconsciousness. By implication, it can refer to “causing rest,” in the sense of “thoughtless/careless.” Also by implication, it can refer to rejoicing the heart, due to it meaning thoughtless/careless. Being drunk can therefore mean all of the above as well.
Proverbs 31:4-7 (KJV) It is not for kings, O Lemuel, it is not for kings to drink wine; nor for princes strong drink:  Lest they drink, and forget the law, and pervert the judgment of any of the afflicted.  Give strong drink unto him that is ready to perish, and wine unto those that be of heavy hearts.  Let him drink, and forget his poverty, and remember his misery no more.
Hosea 14:7 (YLT) Return do the dwellers under his shadow, They revive as corn, and flourish as a vine, His memorial [remembrance] is as wine of Lebanon.
- Wine used for darkening (covering) the eyes.
Genesis 49:12 (LITV) His eyes shall be dark from wine and his teeth white from milk.
- Wine used for causing madness/folly.
Jeremiah 25:15-16 (YLT) ‘For thus said Jehovah God of Israel unto me, Take the wine cup of this fury out of My hand, and thou hast caused all the nations to drink it unto whom I am sending thee;  And they have drunk, and shaken themselves and shewn themselves foolish, because of the sword that I am sending among them.
- Being drunk equated to sleep and being in darkness (not seeing – see definition for Dark/Shade/Shadow).
1 Thessalonians 5:5-8 (KJV) Ye are all the children of light, and the children of the day: we are not of the night, nor of darkness.  Therefore let us not sleep, as do others; but let us watch [be awake] and be sober.  For they that sleep sleep in the night; and they that be drunken are drunken in the night.  But let us, who are of the day, be sober, putting on the breastplate of faith and love; and for an helmet, the hope of salvation.
- Wine [fruit of the vine] is used to represent Jesus’ blood because it is for the “forgiveness (the forgetting) of sins.”
Forgiveness means remembering sins no more.
Hebrews 10:17-18 (LSV) and “I will remember their sins and their lawlessness no more”;  and where [there is] forgiveness of these, there is no longer offering for sin.
Matthew 26:27-29 (LSV) and having taken the cup, and having given thanks, He gave to them, saying, “Drink of it—all;  for this is My blood of the New Covenant, that is being poured out for many, for forgiveness [forgetting] of sins;  and I say to you that I may not drink from now on this produce of the vine, until that day when I may drink it with you new in the kingdom of My Father.”
- Wine used for rejoicing the heart (due to being thoughtless/careless).
Zechariah 10:7 (KJV) And they of Ephraim shall be like a mighty man, and their heart shall rejoice as through wine: yea, their children shall see it, and be glad; their heart shall rejoice in the LORD.
Joel 1:10-12 (KJV) The field is wasted, the land mourneth; for the corn is wasted: the new wine is dried up… The vine is dried up, and the fig tree languisheth; the pomegranate tree, the palm tree also, and the apple tree, even all the trees of the field, are withered: because joy is withered away from the sons of men.
Psalms 104:15 (KJV) And wine that maketh glad the heart of man, and oil to make his face to shine, and bread which strengtheneth man’s heart.